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BIB_140

AMPK-α1 degradation drives BRAF inhibitor resistance and arginine-deprivation sensitivity in melanoma. PMID 29094484 (2017). Molecular basis for arginine-deprivation therapy in BRAF-resistant disease; reinforces precautionary L-arginine avoidance. [Tasks: 13, 15, 18] Tier: 3 Grade: B Retrieved: 2026-05-07

Evidence grade

B

Tier

3

Cited by tasks

13, 15, 18

Identifiers

PMID:29094484

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Full extracted findings & patient-implication analysis: bibliography/BIB_140/findings.md (research corpus). This page is a short context summary — not individualised medical advice.