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BIB_181

Tawbi HA et al. Combined Nivolumab + Ipilimumab in Melanoma Metastatic to the Brain (CheckMate-204). NEJM 2018;379(8):722–730. PMID 30134131. Intracranial ORR ~55%, 3-yr OS ~70% asymptomatic cohort. Practice-changing for melanoma brain metastases. [Tasks: 18] Tier: 1 Grade: A Retrieved: 2026-05-07

Evidence grade

A

Tier

1

Cited by tasks

18

Identifiers

PMID:30134131

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Full extracted findings & patient-implication analysis: bibliography/BIB_181/findings.md (research corpus). This page is a short context summary — not individualised medical advice.