BIB_378
Alcohol consumption and cutaneous melanoma risk — evidence synthesis 2023–2025: NIH-AARP 2025 prospective (n=469,828; HR 1.17 for >3 drinks/day; MM HR 1.14, MIS HR 1.21); Gandini 2018 meta-analysis (20 studies, n=10,555 cases; SRR 1.29 highest vs lowest; dose-response +7% risk per 10 g/day); Rivera 2016 pooled analysis (n=3 US cohorts; TRUNK melanoma HR 1.73 for ≥20 g/day — directly relevant to this patient's right-flank lesion); EPIC 2023 European cohort (n=450,112, 15 yr; lifetime spirits → melanoma HR 1.47 in men); Xu 2023 Mendelian randomisation (OR 2.23, 95%CI 1.11–4.47, p=0.02 — causal d…
- Evidence grade
- B
- Tier
- 2 (NIH-AARP 2025 J Nutr — lar
- Cited by tasks
- 10, 11, 13a, 21
- Identifiers
- PMC5137801 · DOI:10.1016/j · PMID:27909090
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Full extracted findings & patient-implication analysis: bibliography/BIB_378/findings.md (research corpus). This page is a short context summary — not individualised medical advice.