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BIB_409

Aduse-Poku 2025 — RCT-only meta-analysis of smoking-cessation interventions in cancer patients: OPERATIONALISES BIB400's flagged "if smoker, cessation is the single highest-leverage modifiable lever" by supplying the missing efficacy + modality evidence. KEY: cessation interventions work in cancer patients (RR 1.36, 95% CI 1.22–1.51; biochemically-verified RR 1.57, 1.32–1.87), but BEHAVIOURAL-ADVICE-ALONE is NOT sufficient (OR 1.08, 95% CI 0.74–1.60, NS) — only COMBINED pharmacological + behavioural support with ≥5 contacts is reliably effective. Converts BIB400's "add cessation as a top act…

Evidence grade

A

Tier

1 (RCT-only systematic review/meta-analysis, 23 RCTs, Cochrane ROB-2; first RCT-

Cited by tasks

10, 11, 21, 24, 25

Identifiers

PMC12716162

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Full extracted findings & patient-implication analysis: bibliography/BIB_409/findings.md (research corpus). This page is a short context summary — not individualised medical advice.