`BIB_412`

Fasting / fasting-mimicking diet (FMD) / ketogenic / caloric restriction in cancer — evidence anchor for TASK31 (patient asked to split fasting into approaches). Bottom line: fasting-based diets are an INVESTIGATIONAL, ADJUNCTIVE concept studied mostly alongside chemo/immunotherapy in OTHER cancers (breast, colorectal) for tolerability + metabolic/immune effects — early-phase, safe/feasible, NOT curative, NO localised-melanoma or Stage-IB data. Mechanism (differential stress resistance, ↓IGF-1/insulin/mTOR, autophagy, immune modulation) is preclinical-strong / clinical-unproven. For a surgica…

Evidence grade: D
Tier: 2 (authoritative scopin
Cited by tasks: 10, 13a, 26, 31
Identifiers: PMC13074936

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Full extracted findings & patient-implication analysis: bibliography/BIB_412/findings.md (research corpus). This page is a short context summary — not individualised medical advice.